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GeneGo Inc genego metacore
Genego Metacore, supplied by GeneGo Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/genego+metacore/genego+metacore/pm40581639-251-22-22
Average 90 stars, based on 1 article reviews

genego metacore - by Bioz Stars, 2026-09

90/100 stars

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Stable Transfection:

Article Title: Controlling therapeutic protein expression via inhalation of a butter flavor molecule.
Article Snippet: Precise control of the delivery of therapeutic proteins is critical for geneand cell-based therapies, and expression should only be switched on in the presence of a specific trigger signal of appropriate magnitude.. Focusing on the advantages of delivering the trigger by inhalation, we have developed a mammalian synthetic gene switch that enables regulation of transgene expression by exposure to the semivolatile small molecule acetoin, a widely used, FDAapproved food flavor additive.. The gene switch capitalizes on the bacterial regulatory protein AcoR fused to a mammalian transactivation domain, which binds to promoter regions with specific DNA sequences in the presence of acetoin and dose-dependently activates expression of downstream transgenes.

RNA Sequencing:

Article Title: Xenoline-polarized macrophages as an alternative in vitro model of tumor-associated macrophages in glioblastoma.
Article Snippet: .. Altered RNA-seq genes (LFC > 2.0; pAdj < 0.005) and altered kinases (mean final score > 2.0) were combined and analyzed via GeneGo MetaCore to generate literature annotated networks. ..

Article Title: Xenoline-polarized macrophages as an alternative in vitro model of tumor-associated macrophages in glioblastoma.
Article Snippet: .. Altered RNA-seq genes (LFC > 5.0; pAdj < 0.005) and altered kinases (mean final score > 2.0) were combined and analyzed via GeneGo MetaCore to generate literature annotated networks. ..

Activation Assay:

Article Title: Penetrating Exploration of Prognostic Correlations of the FKBP Gene Family with Lung Adenocarcinoma.
Article Snippet: .. 2023, 13, 49 10 of 17 As a result, annotations of almost all BPs obtain d from GeneGo Metacore showed that genes coexpressed with FKBP10 participated in several networks and cell‐cycle‐related pathways such as ʺUbiquinone metabolismʺ, ʺTranslation_(L)‐se‐ lenoaminoacids incorporation in proteins during translationʺ, ʺTranscription_Neg‐ ative regulation of HIF1A functionʺ, ʺOxidative stress_Role of Sirtuin1 and PGC1‐ alpha in activation of antioxidant defense systemʺ, ʺGTP‐XTP metabolismʺ, ʺATP/ITP metabolismʺ, ʺEpithelial cell apoptosis in COPDʺ, ʺApoptosis and sur‐ vival_IL‐17‐induced CIKS‐dependent MAPK signaling pathwaysʺ, ʺCREB1‐de‐ pendent transcription deregulation in Huntingtonʹs diseaseʺ, and ʺSignal transduc‐ tion_Adenosine A1 receptor signaling pathwayʺ (Figure 5, Supplementary Table S6). bers in lung adenocarcinoma (LUAD) patients. ..

other:

Article Title: Prognostic and Immune Infiltration Value of Proteasome Assembly Chaperone (PSMG) Family Genes in Lung Adenocarcinoma
Article Snippet: As a result, annotations of almost all biological processes obtained from GeneGo Metacore showed that genes coexpressed with PSMG1 regulated cell cycle-related pathways such as “Cell cycle_Role of APC in cell cycle regulation”, “Cell cycle_The metaphase checkpoint”, “Ubiquinone metabolism”, “Cell cycle_Spindle assembly and chromosome separation”, and “Cell cycle_Role of Nek in cell cycle regulation” (Figure ; Supplementary ).

Article Title: Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids
Article Snippet: Wilcoxon T-test, experiments were repeated at least three times. d) Representative confocal images of cells expressing SOX2 (red) and Ki67 (green) in DIV30 organoid sections (scalebar 50 μm). e) Pathway enrichment analysis of differentially expressed genes (DEGs) showing enrichment in pathway maps related to cell cycle regulation (Genego Metacore).

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